Mechanism of Action

Zopiclone is a nonbenzodiazepine hypnotic drug used for the treatment of insomnia. It works by enhancing the activity of the neurotransmitter GABA in the brain, it is an inhibitory neurotransmitter that helps to slow down brain activity and promote sleep. Zopiclone specifically binds to the omega-1 receptor subtype of the GABA-A receptor, which enhances the activity of GABA and leads to a decrease in neuronal excitability. This results in a sedative effect, which helps to induce and maintain sleep. You can easily purchase zopiclone if your symptoms are still mild as it has a relatively short half-life, which means it is eliminated from the body quickly, reducing the risk of next-day drowsiness. However, it may still cause sedation, dizziness, and impaired coordination and judgment, so it is important to use it carefully and with the advice of a healthcare professional.

Therapeutic Use

Zopiclone is used for the short-term treatment of insomnia characterized by difficulty in falling asleep, frequent nocturnal awakenings, or early morning awakenings. It works by increasing the activity of a neurotransmitter called GABA, which helps to promote sleep. It can also be used to help people who wake up frequently during the night or who wake up too early.

Drug Interaction of Zopiclone With Other Drugs

Zopiclone may interact with other medications, including prescription and over-the-counter drugs, vitamins, and herbal supplements. Zopiclone can interact with a number of other drugs, including:

CNS depressants (such as alcohol, opioids, and antihistamines) can increase the sedative effects of zopiclone and increase the risk of drowsiness and respiratory depression.

CNS stimulants (such as amphetamines and caffeine) can decrease the effectiveness of zopiclone and increase the risk of insomnia. Monoamine oxidase inhibitors (MAOIs) can interact with zopiclone and increase the risk of serious side effects, such as serotonin syndrome. Tell your doctor first about the medicines you are already taking and do not purchase zopiclone without the permission of your doctor.

Dose and Dosage Form

The usual adult dose is 7.5 mg taken orally immediately before bedtime. The dose may be increased to a maximum of 15 mg per day, but this should only be done under the supervision of a healthcare professional. The drug comes in tablet form and should be taken with a full glass of water. It is important to note that zopiclone should only be used for a short period of time (typically 2-4 weeks) as prolonged use can lead to physical and psychological dependence. 

Dependence on Zopiclone

Zopiclone, like other hypnotic medications, has the potential to cause dependence with prolonged use. Dependence occurs when the body becomes accustomed to the presence of the drug and withdrawal symptoms occur when the drug is discontinued. Withdrawal symptoms can include insomnia, anxiety, irritability, and agitation. As there are risks of dependence so do not purchase zopiclone by your own choice and before buying consult your doctor.

The risk of dependence is higher with long-term use, and when higher doses are used. It is recommended that zopiclone should only be used for short-term treatment of insomnia and should not be used for more than 7 to 10 consecutive days.

Expert Adverse

You can easily purchase zopiclone from Super Meds as we provide medicines with high efficiency and this drug is taken before going to bed for getting rid of insomnia but only on the prescription of your doctor. The drug should not be withdrawn immediately and also not use for more than 7 to 10 days to avoid dependence.